Despair and Loss of Hope in Allah's Mercy

وَٱلَّذِينَ كَفَرُوا۟ بِـَٔايَـٰتِ ٱللَّهِ وَلِقَآئِهِۦٓ أُو۟لَـٰٓئِكَ يَئِسُوا۟ مِن رَّحْمَتِى وَأُو۟لَـٰٓئِكَ لَهُمْ عَذَابٌ أَلِيمٌ

And the ones who disbelieve in the signs of Allāh and the meeting with Him - those have despaired of My mercy, and they will have a painful punishment.